Phospho smad3

Author: lvdg

August undefined, 2024

WebJan 7, 2024 · Recombinant Anti-Smad3 (phospho S423 + S425) antibody. Catalog Number: ab52903. Clone Number: EP823Y. Info:Supplier Page View Product Specs View Product. … WebSpecificity ab51451 is specific for the phosphorylated form of the protein although minimal reactivity with nonphosphorylated human Smad3 can be observed by ELISA and WB. ab51451 also reacts with phosphorylated Smad1 and Smad5 but negligible reactivity is seen against other phosphorylated Smad family members. Tested applications

Anti-SMAD1/3/5 (phospho S423 + S425) antibody (ab51451)

WebMar 21, 2024 · SMAD3 (SMAD Family Member 3) is a Protein Coding gene. Diseases associated with SMAD3 include Loeys-Dietz Syndrome 3 and Aortic Aneurysm, Familial … WebApr 7, 2024 · Moreover, deletion of Smad3 from db/m or db/db mice almost competitively blocked SARS-CoV-2 N-induced Ripk3/MLKL expression and phospho-MLKL level (Fig. 1v, … line printer is impact or nonimpact

Full article: Phospho-specific Smad3 signaling - Taylor & Francis

WebDec 30, 2024 · Phosphorylated forms (phospho-isoforms) in Smad-related pathways can transmit opposing signals: cytostatic C-terminally-phosphorylated Smad3 (pSmad3C) and … WebNov 4, 2024 · Transfection of constitutive active Smad3 could also increase p21 expression, suggesting p21 expression is controlled by the TGF-β1-Smad3 pathway (Fig. 3a,c). However, TGF-β1 did not affect p16 ... WebPhospho-Smad3 (Ser423/425) (D12E11) Rabbit mAb recognizes endogenous levels of Smad3 protein when phosphorylated at Ser422 only, at both Ser423 and Ser425, or at Ser422, Ser423, and Ser425. This antibody also weakly recognizes the equivalent phospho-residues of Smad2 protein (Ser464, Ser465, and Ser467). Species Reactivity: line pricing example

Phospho-Smad2 (Ser465/467)/Smad3 (Ser423/425) …

WebSMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. WebMay 5, 2024 · p-Smad3 Antibody (1D9) is an IgG mouse monoclonal p-Smad3 antibody suitable for the detection of Ser 425 phosphorylated Smad3 of mouse, rat and human … line prep and dishwasher job positionWebAnti-Smad2 (phospho T8) + Smad3 (phospho T8) antibody [EPR23682-64] Description Rabbit monoclonal [EPR23682-64] to Smad2 (phospho T8) + Smad3 (phospho T8) Host species Rabbit Tested applications Suitable for: ICC/IF, Dot blot, IP, WB more details Unsuitable for: Flow Cyt or IHC-P Species reactivity Reacts with: Mouse, Rat, Human … hot to mind nfts

"WebPhospho-Smad3 (S423/S425)/Smad2 (S465/S467) Cell-Based ELISA Summary. Alternatively. * Alternatively, this assay can be run over two days, which requires 2 hours … " - Phospho smad3

Phospho smad3

WebSMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. … WebMay 16, 2024 · Smad3-dependent phagocytosis is mediated, at least in part, through induction of Mfge8 (milk fat globule-epidermal growth factor factor 8), whereas Smad3-mediated PPAR (peroxisome proliferator-activated receptor) upregulation may be involved in acquisition of anti-inflammatory properties. Methods

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WebThe Phospho-SMAD3 (Ser423/425) assay measures SMAD3 when phosphorylated at Ser423/425. Contrary to Western Blot, the assay is entirely plate-based and does not … WebSmad3 and phospho-Smad3 are potential markers of invasive nonfunctioning pituitary adenomas Chunhui Liu,1,2 Zhenye Li,1–3 Dan Wu,4 Chuzhong Li,1–3 Yazhuo Zhang1–3 1Beijing Neurosurgical Institute, Capital Medical University, 2Beijing Institute for Brain Disorders, Brain Tumor Center, 3Department of Neurosurgery, Beijing Tiantan Hospital, …

WebThe SMAD3 gene provides instructions for making a protein involved in transmitting chemical signals from the cell surface to the nucleus. This signaling pathway, called the transforming growth factor-beta (TGF-β) pathway, allows the environment outside the cell to affect cell function, including how the cell produces other proteins. WebJul 1, 2012 · Smad3 is a critical intracellular mediator of TGFβ signaling regulated through phosphorylation by the TGFβ receptor complex at the C terminus. Smad3 is also a …

WebA Life Sciences and Diagnostics business focused on enabling scientists and healthcare professionals to advance research, discovery and detection to improve global health Analytical & Enterprise Solutions An Analytical and Enterprise solutions business, including leading OneSource laboratory services, focused on accelerating scientific outcomes WebJul 1, 2012 · This discovery has expanded the understanding of the significance and complexity of TGFβ signaling through Smads. This review highlights recent advances …

WebMar 13, 2024 · Taken together with the elevated phospho-Smad3 levels in T2D islets (Fig. 7a, b), these findings are consistent with an autocrine role for TGF-β1 in β-cell apoptosis.

WebAlthough the upregulation of Smad3 in VSMCs had no significant effect on total p27 levels, Smad3 did stimulate the phosphorylation of p27 at serine-10 as well as the nuclear export of p27, events associated with cell proliferation. line printing on paperWebPurity/Specificity. Anti-SMAD3 pT179 affinity-purified antibody is directed against the phosphorylated form of human Smad3 protein at the pT179 residue. The product was affinity purified from monospecific antiserum by immunoaffinity purification. Antiserum was first purified against the phosphorylated form of the immunizing peptide. line practice worksheetsWebThis antibody is phospho specific for dual phosphorylated pS423 and pS425 of Smad3. Stimulation with 2 ng/ml TGF-beta for 1 hour is suggested. Purity/Specificity. This affinity … hot tom oil