WebFurther, polymorphisms in IL-28B (rs12979860, rs12980275, and rs8099917) were assessed by real-time polymerase chain reaction in all groups. Results: The IL-28B rs12979860 CC and rs12980275 AA genotypes were significantly associated with SR of HCV infection and response to therapy, whereas the C allele of IL-6 (–174) was … Web3 nov. 2024 · We performed additional analyses of those published data to examine whether IFNL4 rs12979860 genotype predicted relapse after 8 weeks of treatment with this …
Scilit Article - Interferon-λ rs12979860 genotype association with ...
Web3 mrt. 2024 · In this study, we have found that the rs12979860 polymorphism in IFNL4 was also associated with the presence of symptomatic SARS-CoV-2 infection. Thus, the T allele of rs12979860 was significantly overrepresented in COVID-19 patients regarding non-COVID-19 controls, suggesting that this allele may be a risk factor for COVID-19. WebThe genetic variant rs12979860, located in the INFL4 gene, is a strong predictor of response to peginterferon-based therapies. The variant is a C to T change—individuals with the favorable "C/C" genotype have about a 2-fold higher likelihood of achieving SVR compared to individuals with CT or TT genotypes. kern county ca probation
rs12979860 - SNPedia
WebThe ability to produce IFNL4 (i.e., carriage of IFNL4 rs12979860 CT or TT genotype), in addition to male gender, absent/mild steatosis, and lower viral load, augments antibody … Web6 sep. 2024 · Only 1.2% of patients with IFNL4 rs12979860-CC genotype relapsed, compared to 5.9% of patients with IFNL4 rs12979860-CT and 4.9% of patients with IFNL4 rs12979860-TT genotype. Patients with an unfavorable IFNL4 rs12979860 genotype (CT or TT) were almost five times more likely to relapse than those with the IFNL4 rs12979860 … Web4 okt. 2024 · IFNL4 genotyping showed that 18% of patients carried the CC genotype at rs12979860 while 49 and 33% of patients, respectively, carried CT and TT genotypes . … kern county career service center