Web30 de jan. de 2010 · We consider the situation of testing hierarchically a (key) secondary endpoint in a group-sequential clinical trial that is mainly driven by a primary endpoint. By 'mainly driven', we mean that the interim analyses are planned at points in time where a certain number of patients or events have accru … WebHá 2 dias · Hierarchical system definition: A hierarchical system or organization is one in which people have different ranks or... Meaning, pronunciation, translations and examples
Hierarchical testing of multiple endpoints in group-sequential …
Web27 de set. de 2024 · Also called Hierarchical cluster analysis or HCA is an unsupervised clustering algorithm which involves creating clusters that have predominant ordering from top to bottom. For e.g: All files and folders on our hard disk are organized in a hierarchy. The algorithm groups similar objects into groups called clusters. Web30 de jan. de 2010 · We consider the situation of testing hierarchically a (key) secondary endpoint in a group-sequential clinical trial that is mainly driven by a primary … bir change of rdo requirements
Corporate Hierarchy: Definition, How It Works, and Configuration
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