WebMay 8, 2024 · Grapefruit can increase the side effects of some statin cholesterol medications, causing muscle damage. 4–7: Certain blood pressure medications Most types of blood pressure medicines are not ... Only certain statin medications interact negatively with grapefruit. This is an issue only for lovastatin (Mevacor) and simvastatin (Zocor, or Vytorin) and typically is only problematic at the highest dosages. Alternative statins like rosuvastatin (Crestor), pravastatin (Pravachol), pitavastatin (Livalo) or fluvastatin … See more The introduction of statin medications has helped patients: 1. Lower LDL (Low-density lipoprotein cholesterol or “bad” cholesterol). 2. Lower risk for blood vessel disease. 3. Avoid a second heart attack if they have … See more Grapefruit contains a chemical that can interfere with your body’s ability to break down or metabolize certain statin medications. When statin takers eat large amounts of … See more

Grapefruit Juice and Statins - The American Journal …

WebIf the juice is taken 12 hours before these statins, the reductions are, respectively, 43% and 66%, and for atorvastatin, 42% and 66%. The increased rhabdomyolysis risk from … WebAlthough grapefruit is mostly water, it is a very healthy food, with high levels of vitamins, minerals and nutrients. Grapefruit Nutrition. Fiber. Grapefruit, like other … how is ops calculated

Grapefruit juice and statins - Harvard Health

WebJan 17, 2024 · But grapefruit's reputation for interfering with some medications is well-deserved. It particularly affects certain anti-cholesterol statin drugs, as well as some … WebFor example, if you drink a lot of grapefruit juice while taking certain statin drugs to lower cholesterol, too much of the drug may stay in your body, increasing your risk for liver and muscle damage that can lead to kidney failure. Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. WebApr 17, 2024 · Importantly, grapefruit affects certain statins more than others, as Harvard Health Publishing points out. It has a big impact on atorvastatin (Lipitor), lovastatin … how is opium used