Cisplatin ic50

Author: ljyd

August undefined, 2024

WebFeb 28, 2024 · All the new complexes showed cytotoxicity in vitro against the three cancer cell lines, but only complex 1a showed statistically significant different activity compared …

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WebApr 2, 2024 · IC50 values for ( a–d) bortezomib- and ( e–h) cisplatin-treated MCF7, HCC38, MCF-10A, and MDA-MB-436 breast cancer cells … WebJun 5, 2024 · E Cell viability of A2780 cells and resistant cells (A2780-CDDP) after were treated with cisplatin at corresponding concentrations for 48 h was detected by CCK-8 assay. Half maximal inhibitory... thea cambert inn vermont

Cisplatin remodels the tumor immune microenvironment via …

WebSep 1, 2015 · Cisplatin, an alkylating agent has been successfully used since decades for the treatment of variety of cancers viz. bone cancer, lung cancer, head and neck cancer, … WebFeb 5, 2016 · Cisplatin remains to be primary chemotherapeutic drug for gastric cancer patients, especially for advanced stage ones. However, primary or acquired resistance … WebDownload scientific diagram Summary of IC50 values of sinomenine or cisplatin in gastric cancer cells. from publication: Sinomenine sensitizes human gastric cancer cells to … the aca marketplace

Hederagenin potentiated cisplatin- and paclitaxel …

Table 1 IC50 of cisplatin in various cell line. IC50 cisplatin...

WebCombination therapy of cisplatin and resveratrol to induce cellular aging in gastric cancer cells: Focusing on oxidative stress, and cell cycle arrest . × Close Log In. Log in with Facebook Log in with Google. or. Email. Password. Remember me on this computer. or reset password. Enter the email address you signed up with and we'll email you a ... WebBioAssay record AID 625684 submitted by ChEMBL: Ratio of cisplatin IC50 to compound IC50 for mouse B16F10. the acai berryWebThe IC(50) was defined as the drug concentration required for a 50% reduction in optical density. Cytotoxicity assays were performed with four sequential combinations of a … thea cambert rooftop garden mysteries

"WebFor comparison, cisplatin, a common clinical drug for bladder cancer, showed IC 50 values of 1.33 and 4.98 µg/mL for T24 and J82 cells at 48 h CCK-8 assay, respectively [27]. Cisplatin also... " - Cisplatin ic50

Cisplatin ic50

Comparative evaluation of cisplatin and carboplatin sensitivity in ...

WebJan 10, 2024 · The half maximal inhibitory concentration (IC50) of different OC cells after treatment with ( a) olaparib, ( b) niraparib and ( c) rucaparib, assessed by clonogenic assays. Data represents the mean ± SEM of triplicates of … WebFeb 1, 2024 · Cisplatin injection is used to treat advanced cancer of the bladder, ovaries, or testicles. Cisplatin is an antineoplastic agent (cancer medicine). It interferes with the growth of cancer cells, which are eventually destroyed by the body. This medicine is to be given only by or under the direct supervision of a doctor.

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WebBackground: Cisplatin (Cp) is an antineoplastic agent with a dose-limiting nephrotoxicity. Cp-induced nephrotoxicity is characterized by the interplay of oxidative stress, inflammation, and apoptosis. WebCisplatin (DDP) is a common therapeutic option for non-small cell lung carcinoma (NSCLC). However, some patients fail to respond to the DDP chemotherapy. Therefore, identifying novel biomarkers to improve the diagnosis and treatment of NSCLC is important.

WebApr 11, 2024 · Group division and overview of cells’ IC50 value of cisplatin 661 cell lines were finally enrolled with the complete data of mRNA, microRNA expression, and metabolite. They were divided into 3 groups according to the IC50 value, the half inhibitory concentration, given by the CCLE database, which reflects the sensitivity to … WebAfter an incubation with DDP/EXOs, the cell lines exhibited a higher IC50 value for cisplatin, P-gp expression, migration and invasion capabilities and a lower apoptosis …

WebJun 15, 2024 · Methods: In this study, real-time quantitative PCR (RT-qPCR) and Western blotting (WB) were performed for detecting the expressions of miR-133b, fibroblast growth factor receptor 1 (FGFR1), and Wingless/Integrated (Wnt)-β-catenin pathway markers (Wnt1, β-catenin, nuclear-β-catenin, p-GSK-3β, GSK-3β, cyclinD1, and FOXQ1). WebIC 50 values for cisplatin, curcuminoid, and combination treatments in A549 cell culture. Standard deviation values are provided after the ± symbol for each inhibitory …

WebOct 25, 2016 · To overcome severe MTT artifacts, we developed an unbiased direct IC50 measurement method, the limiting dilution assay. This detection technique led us to the …

WebAug 13, 2024 · CCK8 assay demonstrated that the half-maximal inhibitory concentration (IC50) of paclitaxel was 22.61 nM and 101.4 nM for NCI-H1975 and NCI-H1299 cells, … thea capazziWebIC50 values were calculated. Evaluation of apoptosis and DNA damage were performed. In addition, the expression of pro-apoptotic and anti-apoptotic genes and proteins were tested. IC50 values indicated less toxicity of the Schiff base … thea cameraWebOverexpressing miR-515-5p markedly reduced cisplatin and 5-Fu IC50 values in HK-1/CDDP and CNE-1/CDDP cells, while IL-25 transfection was sufficient to reverse this phenotype (Figure 4E and F). As such, our data demonstrate that circNRIP1 enhances 5-Fu and cisplatin resistance in NPC cells at least in part via sequestering miR-515-5p and ... thea cambert